GlycoBac's technology has been developed in Dr. Jarvis' lab at the University of Wyoming. Links to some of the peer-reviewed papers that describe GlycoBac's technology are listed on the right.
A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production (2018)
Adventitious viruses in insect cell lines used for recombinant protein expression (2017)
Infectivity of Sf-rhabdovirus variants in insect and mammalian cell lines (2017)
Rhabdovirus-like endogenous viral elements in the genome of Spodoptera frugiperda insect cells are actively transcribed: Implications for adventitious virus detection (2016)
Characterization of an Sf-rhabdovirus-negative Spodoptera frugiperda cell line as an alternative host for recombinant protein production in the baculovirus-insect cell system (2016)
Engineering β1,4-galactosyltransferase I to reduce secretion and enhance N-glycan elongation in insect cells (2015)
Innovative use of a bacterial enzyme involved in sialic acid degradation to initiate sialic acid biosynthesis in glycoengineered insect cells (2012)
Impact of a human CMP-sialic acid transporter on recombinant glycoprotein sialylation in glycoengineered insect cells (2012)
Substrate Specificities and Intracellular Distributions of Three N-glycan Processing Enzymes Functioning at a Key Branch Point in the Insect N-Glycosylation Pathway (2012)
Insect cell glycosylation patterns in the context of biopharmaceuticals (2009)
A new glycoengineered insect cell line with an inducibly mammalianized protein N-glycosylation pathway (2009)
Isolation and analysis of a baculovirus vector that supports recombinant glycoprotein sialylation by SfSWT-1 cells cultured in serum-free medium (2006)
A transgenic insect cell line engineered to produce CMP–sialic acid and sialylated glycoproteins (2003)
Engineering the protein N-glycosylation pathway in insect cells for production of biantennary, complex N-glycans (2002)
Stable expression of mammalian β1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells (1998)
Modifying the insect cell N-glycosylation pathway with immediate early baculovirus expression vectors (1996)